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The ultimate aim of cancer research is to eliminate this common and devastating disease from the human population. To develop more effective prevention methods we need to understand what triggers carcinogenesis. To diagnose precancerous lesions and early-stage cancers quickly and accurately we need to detect the earliest molecular changes leading to each type of cancer. To determine a patient's prognosis we need to appreciate which molecular changes affect tumour growth rate and invasiveness. And to tailor therapies to individual tumours we need to understand the fundamental differences, not only between a cancer cell and a 'normal' cell, but also between one cancer cell and another. All of these goals depend on a combination of basic and applied research. Nature Reviews Cancer will be a gateway from which cancer researchers — from those investigating the molecular basis of cancer to those involved in translational research — access the information that they need to further the ability to diagnose, treat and ultimately prevent cancer.Subjects covered * Genomic instability: chromosomal and microsatellite instabilities; defects in DNA repair pathways. * Growth factor signalling to cell cycle progression: proto-oncogenes and their dysregulation. * Growth inhibitory signals: dysregulation of quiescence and differentiation, tumour suppressors and their inactivation. * Cellular immortality and telomere maintenance. * Cell death: evading apoptosis, including avoidance of immune surveillance systems. * Angiogenesis: sustaining tumour growth by building a vascular system. * Metastasis: moving to and surviving in new environments. * Carcinogenesis and cancer prevention: epidemiology, genetic and environmental triggers, gene–environment interactions and strategies for reducing risk. * Cancer diagnosis and prognosis: molecular markers; diagnostic imaging; defining tumour margins; detecting minimal residual disease. * New approaches to cancer therapy: rational drug design, gene therapy, immunotherapy, combination therapies, combating drug resistance and targeting therapies to the individual. * Experimental systems and techniques: cell culture and animal models, genomic and proteomic approaches to studying cancer. * Cancer-associated disease: cancer pain, cachexia, symptoms associated with treatment (hair loss, anaemia, gastrointestinal disease), psychosocial aspects of cancer. * Ethical, legal and social issues surrounding cancer research: trial design, genetic screening, public and professional education, research policy and advocacy. * Conventional approaches to cancer diagnosis and treatment: how do they perform, what are their drawbacks and how might they be improved in the future?.

Neoplasia encourages the free exchange of all clones, cell lines, and biological reagents described in its pages to facilitate the progress of research in order to ultimately provide those fighting neoplastic diseases with new diagnostic, preventative and therapeutic options.

Published monthly from January 2010, Neuro-Oncology is the official journal of the Society for Neuro-Oncology. Also affiliated with the Japan Society for Neuro-Oncology and the European Association for Neuro-Oncology it is a truly global journal in the field.Dedicated to providing superior and rapid publication of information in all areas of neuro-oncology, the journal contains peer-reviewed articles and reviews, symposia on selected topics, published abstracts of annual meetings, and society news and announcements from around the world.

Nitric Oxide: Biology and Chemistry includes original research, methodology papers and reviews relating to nitric oxide and other gasotransmitters such as hydrogen sulfide and carbon monoxide. Special emphasis is placed on the biological chemistry, physiology, pharmacology, enzymology and pathological significance of these molecules in human health and disease. The journal also accepts manuscripts relating to plant and microbial studies involving these molecules.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com

Nuclear Medicine and Biology publishes original research addressing all aspects of radiopharmaceutical science: synthesis, in vitro and ex vivo studies, in vivo biodistribution by dissection or imaging, radiopharmacology, radiopharmacy, and translational clinical studies of targeted radiotracers. The importance of the target to a key disease should be the first consideration. If the synthesis of a new radiopharmaceutical is submitted without in vitro or in vivo data, then the uniqueness of the chemistry must be emphasized.These multidisciplinary studies should validate the mechanism of localization whether the probe is based on binding to a receptor, enzyme, tumor antigen, or another well-defined target. The studies should be aimed at evaluating how the chemical and radiopharmaceutical properties affect pharmacokinetics, pharmacodynamics, or therapeutic efficacy. Ideally, the study would address the sensitivity of the probe to changes in disease or treatment, although studies validating mechanism alone are acceptable. Radiopharmacy practice, addressing the issues of preparation, automation, quality control, dispensing, and regulations applicable to qualification and administration of radiopharmaceuticals to humans, is an important aspect of the developmental process, but only if the study has a significant impact on the field.Contributions on the subject of therapeutic radiopharmaceuticals also are appropriate provided that the specificity of labeled compound localization and therapeutic effect have been addressed. Supplemental information on the Aims and Scope can be found in the Jan issue of the Journal and at www.nucmedbio.com.

This timely publication reports and reviews current findings on the effects of nutrition on the etiology, therapy, and prevention of cancer. Etiological issues include clinical and experimental research in nutrition, carcinogenesis, epidemiology, biochemistry, and molecular biology. Coverage of therapy focuses on research in clinical nutrition and oncology, dietetics, and bioengineering. Prevention approaches include public health recommendations, preventative medicine, behavior modification, education, functional foods, and agricultural and food production policies. Peer Review Policy: All research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymous refereeing by two experts in the field. Publication office: Taylor & Francis, Inc., 325 Chestnut Street, Suite 800, Philadelphia, PA 19106.

Oncogene covers all aspects of the structure and function of oncogenes, especially: * Cellular oncogenes and their mechanism of activation * Structure and function of their encoded proteins * Oncogenes of the DNA and RNA tumour viruses * The molecular oncology of human tumours * Tumour suppressor genes * Growth regulatory genes * Cell cycle control * Growth factors and receptors * Apoptosis * Immortalisation and cellular senescence.

Brought to you by the editorial team of Oncogene, Oncogenesis is a peer-reviewed online journal that publishes full-length papers exploring the molecular basis of cancer and related phenomena. It seeks to promote diverse and integrated areas of molecular biology, cell biology, oncology, and genetics.

The field of haemostasis and thrombosis has witnessed significant developments during the last few decades. While the upcoming of biochemistry, cell biology and later of molecular biology as new research tools has constantly been reflected in the journal, it nevertheless continues to devote many of its pages to traditional clinical pathophysiology.The journal features original contributions reporting the latest findings on the pathology, physiology and biochemistry of haemorrhagic disease and thrombosis as well as on their diagnosis and treatment. In addition to in-depth studies of such topics as blood coagulation factors, fibrinolysis, platelets and vascular biology, readers will find extensive data on clinical results with heparin, oral anticoagulants and newer anti-thrombotics.These experimental and clinical investigations are supported by occasional authoritative reviews to make the journal a full record of current research on thrombosis and haemostasis and its clinical implications.

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Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics publishes research of the highest quality that contributes to an understanding of cancer in areas of molecular biology, cell biology, biochemistry, biophysics, genetics, biology, endocrinology, and immunology, as well as studies on the mechanism of action of carcinogens and therapeutic agents, reports dealing with cancer prevention and epidemiology, and clinical trials delineating effective new therapeutic regimens.

Oncology Research and Treatment offers an interdisciplinary forum for cancer research and treatment. Peer-reviewed original and review articles cover a wide range of aspects in medical hematology and oncology, surgical, gynecological, pediatric, and urological oncology, dermatological oncology, diagnostics, radiation oncology, psychological care, pathology, clinical-translational oncology, and oncological rehabilitation. Oncology Research and Treatment is addressed to clinicians and practitioners working and researching in the field of hematology and oncology.
The focus of Oncology Research and Treatment is to report clinical and translational research. Basic research is not in the scope of the journal.

Oral Oncology is an international interdisciplinary journal which publishes high quality original research, clinical trials and review articles, editorials, and commentaries relating to the etiopathogenesis, epidemiology, prevention, clinical features, diagnosis, treatment and management of patients with neoplasms in the head and neck.Oral Oncology is of interest to head and neck surgeons, radiation and medical oncologists, maxillo-facial surgeons, oto-rhino-laryngologists, plastic surgeons, pathologists, scientists, oral medical specialists, special care dentists, dental care professionals, general dental practitioners, public health physicians, palliative care physicians, nurses, radiologists, radiographers, dieticians, occupational therapists, speech and language therapists, nutritionists, clinical and health psychologists and counselors, professionals in end of life care, as well as others interested in these fields.Basic, translational, or clinical Research or Review papers of high quality and that make a contribution to new knowledge are invited on the following aspects of neoplasms arising in the head and neck (including lip, tongue, oral cavity, oropharynx, salivary glands, sinuses, nose, nasopharynx, larynx, skull base, thyroid, and craniofacial region, and the related hard and soft tissues and lymph nodes):• Etiopathogenesis: natural history of cancer and pre-cancer; basic pathology, metastatic mechanisms; genetic changes; cellular and molecular changes; microorganisms; growth factors, adhesion and other molecules• Epidemiology; risk factors; biomarkers; protective factors; geographic factors; prevention; screening and intervention• Clinical features; orofacial effects of neoplasms at both local and distant sites; tumor staging and grading• Diagnosis; detection of cancer and pre-cancer; cellular and molecular markers for diagnosis; advances in imaging and other functional diagnostic modalities for cancer and pre-cancer• Management and Prognosis; clinical, cellular and molecular markers for prognosis; treatment options including surgical, lasers, photodynamic therapy, cryosurgery, micro- vascular and other forms of surgery, medical, radiotherapy, chemotherapy, immunotherapy, biological and gene therapy advances; molecular targets and new therapeutics (new cytotonics and molecular-targeted therapies); multimodality treatment; advances in reconstruction and rehabilitation, including flaps and grafts, alloplasty, bone and connective tissue biology; multidisciplinary teamwork in cancer care and oral health care.• Quality of life issues; issues of consent; psychosocial aspects; patient and health professional information; patient involvement; psychological interventions, improving outcomes; the prevention, diagnosis and management of complications, including, pain, hemorrhage, dysfunction, deformity, osteoradionecrosis, xerostomia, and others; rehabilitation; palliative and end of life care; and support teamwork.

Genetics and genomics research has grown at a bewildering pace in the past 15 years. The techniques of these fields are being applied to a wealth of biological questions and experimental systems. PLoS Genetics reflects the full breadth and interdisciplinary nature of this research by publishing outstanding original contributions in all areas of biology.PLoS Genetics publishes human studies, as well as research on model organisms—from mice and flies, to plants and bacteria. Our emphasis is on studies of broad interest that provide significant mechanistic insight into a biological process or processes. Topics include (but are not limited to) gene discovery and function, population genetics, genome projects, comparative and functional genomics, medical genetics, disease biology, evolution, gene expression, complex traits, chromosome biology, and epigenetics.Please refer to our Author Guidelines and Frequently Asked Questions when you are preparing manuscripts for submission. If you are unsure whether your work is suitable for PLoS Genetics, you can send a Presubmission Inquiry.

Pathology & Oncology Research (POR) is an interdisciplinary journal at the interface of pathology and oncology, including the preclinical and translational research, diagnostics and therapy. Furthermore, POR offers an international forum for the rapid communication of reviews, original research, critical and topical reports with excellence and novelty. Published quarterly, POR is dedicated to keeping scientists informed of developments in its focused biomedical fields which span the gap between basic research and clinical medicine. A special aim of POR is to promote publishing activity in pathology and oncology of colleagues in the Central and East European region. The journal will interest pathologists, and a broad range of experimental and clinical oncologists, and related experts. Pathology & Oncology Research is supported by distinguished international advisory board and the Arányi Foundation for modern pathology.